Uremia is the buildup of waste and toxic substances in the body. It occurs when the kidneys become damaged and not able to perform filtration to their capacity. The toxins and waste instead of being in the urine end up being in the bloodstream. Such wastes are mainly creatinine and urea. Uremia is a life-threatening condition and a major sign of chronic kidney disease . So, if you have uremia, make sure to begin early treatment with uremia treatment in Ayurveda. Uremia and azotemia Azotemia is another condition caused by damaged kidneys. These two conditions develop at the same time. The only difference is that uremia is the buildup of urea while azotemia means nitrogen buildup in the blood. What are the symptoms of uremia? In the initial stages hardly any sign occur during chronic kidney disease. However, as you progress towards the late stages, kidney damage becomes severe and uremia develops. The following are the signs that may occur during that time: Extreme tiredness